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Immunological evidence for eight spans in the membrane domain of 3- hydroxy-3-methylglutaryl coenzyme A reductase: implications for enzyme degradation in the endoplasmic reticulum

We have raised two monospecific antibodies against synthetic peptides derived from the membrane domain of the ER glycoprotein 3-hydroxy-3- methylglutaryl coenzyme A (HMG-CoA) reductase, the rate limiting enzyme in the cholesterol biosynthetic pathway. This domain, which was proposed to span the ER m...

Täydet tiedot

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Bibliografiset tiedot
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The Rockefeller University Press 1992
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2289486/
https://ncbi.nlm.nih.gov/pubmed/1374417
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