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Synthesis of abnormal immunoglobulins by hybridomas from autoimmune "viable motheaten" mutant mice

Secretory defects in abnormal plasma cells, called Mott cells, that appear in lymphoid tissues of spontaneously autoimmune, "viable motheaten" (mev/mev) mice lead to deposition of immunoglobulin in RER- bound vesicles. Such vesicles have been termed Russel bodies. Cells with Russel bodies...

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Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 1991
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2289055/
https://ncbi.nlm.nih.gov/pubmed/1646823
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