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Specificities and V genes encoding monoclonal autoantibodies from viable motheaten mice

Several hundred hybridomas were obtained from 1-2-mo-old viable motheaten (mev) mice. Among the Ig-secreting hybridomas tested, greater than 50% (17/33) exhibited reactivity for autoantigens, supporting the idea that the Ly-1 B cells that predominate in mev mice contain frequent precursors of autoan...

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Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 1988
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2188884/
https://ncbi.nlm.nih.gov/pubmed/3351435
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