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Novel B-cell maturation factor from spontaneously autoimmune viable motheaten mice.

Both in vivo and in vitro, mice homozygous for the viable motheaten mutation show severe immunodeficiency, polyclonal B-cell activation and Ig secretion, and spontaneous production of a lymphokine [B-cell maturation factor (BMF)] that directly drives the maturation of normal or tumor B cells to the...

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Detalhes bibliográficos
Main Authors: Sidman, C L, Marshall, J D, Masiello, N C, Roths, J B, Shultz, L D
Formato: Artigo
Idioma:Inglês
Publicado em: 1984
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC392105/
https://ncbi.nlm.nih.gov/pubmed/6334306
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