Novel B-cell maturation factor from spontaneously autoimmune viable motheaten mice.

Both in vivo and in vitro, mice homozygous for the viable motheaten mutation show severe immunodeficiency, polyclonal B-cell activation and Ig secretion, and spontaneous production of a lymphokine [B-cell maturation factor (BMF)] that directly drives the maturation of normal or tumor B cells to the...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Sidman, C L, Marshall, J D, Masiello, N C, Roths, J B, Shultz, L D
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1984
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC392105/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6334306/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.22.7199
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