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FTIR reveals structural differences between native β-sheet proteins and amyloid fibrils

The presence of β-sheets in the core of amyloid fibrils raised questions as to whether or not β-sheet-containing proteins, such as transthyretin, are predisposed to form such fibrils. However, we show here that the molecular structure of amyloid fibrils differs more generally from the β-sheets in na...

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Bibliografiske detaljer
Main Authors: Zandomeneghi, Giorgia, Krebs, Mark R.H., McCammon, Margaret G., Fändrich, Marcus
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2287307/
https://ncbi.nlm.nih.gov/pubmed/15537750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.041024904
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