Loading...
Comparative computational analysis of prion proteins reveals two fragments with unusual structural properties and a pattern of increase in hydrophobicity associated with disease-promoting mutations
Prion diseases are a group of neurodegenerative disorders associated with conversion of a normal prion protein, PrP(C), into a pathogenic conformation, PrP(Sc). The PrP(Sc) is thought to promote the conversion of PrP(C). The structure and stability of PrP(C) are well characterized, whereas little is...
Na minha lista:
| Main Authors: | , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2004
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2287303/ https://ncbi.nlm.nih.gov/pubmed/15557265 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.04833404 |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|