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Thermal stability of human α-crystallins sensed by amide hydrogen exchange

The α-crystallins, αA and αB, are major lens structural proteins with chaperone-like activity and sequence homology to small heat-shock proteins. As yet, their crystal structures have not been determined because of the large size and heterogeneity of the assemblies they form in solution. Because α-c...

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Detalhes bibliográficos
Main Authors: Hasan, Azeem, Yu, Jiong, Smith, David L., Smith, Jean B.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2286712/
https://ncbi.nlm.nih.gov/pubmed/14739319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.03180004
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