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Structural alteration of cofactor specificity in Corynebacterium 2,5-diketo-D-gluconic acid reductase
Corynebacterium 2,5-Diketo-D-gluconic acid reductase (2,5-DKGR) catalyzes the reduction of 2,5-diketo-D-gluconic acid (2,5-DKG) to 2-Keto-L-gulonic acid (2-KLG). 2-KLG is an immediate precursor to L-ascorbic acid (vitamin C), and 2,5-DKGR is, therefore, an important enzyme in a novel industrial meth...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Cold Spring Harbor Laboratory Press
2004
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2286697/ https://ncbi.nlm.nih.gov/pubmed/14718658 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.03450704 |
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