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Evaluation of the food grade expression systems NICE and pSIP for the production of 2,5-diketo-D-gluconic acid reductase from Corynebacterium glutamicum

2,5-diketo-D-gluconic acid reductase (2,5-DKG reductase) catalyses the reduction of 2,5-diketo-D-gluconic acid (2,5-DKG) to 2-keto-L-gulonic acid (2-KLG), a direct precursor (lactone) of L-ascorbic acid (vitamin C). This reaction is an essential step in the biocatalytic production of the food supple...

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Bibliographic Details
Main Authors: Kaswurm, Vanja, Nguyen, Tien-Thanh, Maischberger, Thomas, Kulbe, Klaus D, Michlmayr, Herbert
Format: Artigo
Language:Inglês
Published: Springer 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3565945/
https://ncbi.nlm.nih.gov/pubmed/23356419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2191-0855-3-7
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