Llwytho...
Alteration of the tertiary structure of the major bee venom allergen Api m 1 by multiple mutations is concomitant with low IgE reactivity
We have engineered a recombinant form of the major bee venom allergen (Api m 1) with the final goal of reducing its IgE reactivity. This molecule (Api mut) contains 24 mutations and one deletion of 10 amino acids. The successive introduction of these sequence modifications led to a progressive loss...
Wedi'i Gadw mewn:
| Prif Awduron: | , , , , , , , |
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| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
Cold Spring Harbor Laboratory Press
2004
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| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2286571/ https://ncbi.nlm.nih.gov/pubmed/15459335 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.04885404 |
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