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Understanding the determinants of stability and folding of small globular proteins from their energetics

The results of minimal model calculations indicate that the stability and the kinetic accessibility of the native state of small globular proteins are controlled by few “hot” sites. By means of molecular dynamics simulations around the native conformation, which describe the protein and the surround...

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Hlavní autoři: Tiana, Guido, Simona, Fabio, De Mori, Giacomo M.S., Broglia, Ricardo A., Colombo, Giorgio
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2004
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2286534/
https://ncbi.nlm.nih.gov/pubmed/14691227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.03223804
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