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Kinetics of T cell receptor β, γ, and δ rearrangements during adult thymic development: T cell receptor rearrangements are present in CD44(+)CD25(+) Pro-T thymocytes

We performed a comprehensive analysis of T cell receptor (TCR) γ rearrangements in T cell precursors of the mouse adult thymus. Using a sensitive quantitative PCR method, we show that TCRγ rearrangements are present in CD44(+)CD25(+) Pro-T thymocytes much earlier than expected. TCRγ rearrangements i...

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Библиографические подробности
Главные авторы: Capone, Myriam, Hockett, Richard D., Zlotnik, Albert
Формат: Artigo
Язык:Inglês
Опубликовано: The National Academy of Sciences 1998
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC22863/
https://ncbi.nlm.nih.gov/pubmed/9770518
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