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Disruption of TGF-β signaling in T cells accelerates atherosclerosis

Increasing evidence suggests that atherosclerosis is an inflammatory disease promoted by hypercholesterolemia. The role of adaptive immunity has been controversial, however. We hypothesized that proatherogenic T cells are controlled by immunoregulatory cytokines. Among them, TGF-β has been implied i...

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Bibliografiske detaljer
Main Authors: Robertson, Anna-Karin L., Rudling, Mats, Zhou, Xinghua, Gorelik, Leonid, Flavell, Richard A., Hansson, Göran K.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC228445/
https://ncbi.nlm.nih.gov/pubmed/14568988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200318607
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