NADPH oxidase signal transduces angiotensin II in hepatic stellate cells and is critical in hepatic fibrosis

Angiotensin II (Ang II) is a pro-oxidant and fibrogenic cytokine. We investigated the role of NADPH oxidase in Ang II–induced effects in hepatic stellate cells (HSCs), a fibrogenic cell type. Human HSCs express mRNAs of key components of nonphagocytic NADPH oxidase. Ang II phosphorylated p47(phox),...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Bataller, Ramón, Schwabe, Robert F., Choi, Youkyung H., Yang, Liu, Paik, Yong Han, Lindquist, Jeffrey, Qian, Ting, Schoonhoven, Robert, Hagedorn, Curt H., Lemasters, John J., Brenner, David A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2003
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC228420/
https://ncbi.nlm.nih.gov/pubmed/14597764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200318212
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky