Effects of losartan on hepatic expression of nonphagocytic NADPH oxidase and fibrogenic genes in patients with chronic hepatitis C

Angiotensin II promotes liver fibrogenesis by stimulating nonphagocytic NADPH oxidase (NOX)-induced oxidative stress. Angiotensin II type 1 (AT1) receptor blockers attenuate experimental liver fibrosis, yet their effects in human liver fibrosis are unknown. We investigated the effects of losartan on...

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Detalhes bibliográficos
Main Authors: Colmenero, Jordi, Bataller, Ramón, Sancho-Bru, Pau, Domínguez, Marlene, Moreno, Montserrat, Forns, Xavier, Bruguera, Miquel, Arroyo, Vicente, Brenner, David A., Ginès, Pere
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2009
Assuntos:
Liver and Biliary Tract
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2763804/
https://ncbi.nlm.nih.gov/pubmed/19628656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00162.2009
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