Activation of microhelix charging by localized helix destabilization

We report that aminoacylation of minimal RNA helical substrates is enhanced by mismatched or unpaired nucleotides at the first position in the helix. Previously, we demonstrated that the class I methionyl-tRNA synthetase aminoacylates RNA microhelices based on the acceptor stem of initiator and elon...

Полное описание

Библиографические подробности

Опубликовано в::	Proc Natl Acad Sci U S A
Главные авторы:	Alexander, Rebecca W., Nordin, Brian E., Schimmel, Paul
Формат:	Artigo
Язык:	Inglês
Опубликовано:	National Academy of Sciences 1998
Предметы:	Biological Sciences
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22811/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9770466/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.21.12214
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