Activation of microhelix charging by localized helix destabilization
We report that aminoacylation of minimal RNA helical substrates is enhanced by mismatched or unpaired nucleotides at the first position in the helix. Previously, we demonstrated that the class I methionyl-tRNA synthetase aminoacylates RNA microhelices based on the acceptor stem of initiator and elon...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
1998
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22811/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9770466/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.21.12214 |
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