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Solution structure of the human Grb14–SH2 domain and comparison with the structures of the human Grb7–SH2/erbB2 peptide complex and human Grb10–SH2 domain
Grb14 is an adapter protein that is known to be overexpressed in estrogen receptor positive breast cancers, and in a number of prostate cancer cell lines. Grb14 has been demonstrated to bind to a number of activated receptor tyrosine kinases (RTKs) and to modulate signals transduced through these re...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Cold Spring Harbor Laboratory Press
2004
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2280013/ https://ncbi.nlm.nih.gov/pubmed/15322292 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.04884704 |
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