Direct genotypic detection of Mycobacterium tuberculosis rifampin resistance in clinical specimens by using single-tube heminested PCR.

Recent analysis of the gene encoding the beta subunit of Mycobacterium tuberculosis RNA polymerase (rpoB) has demonstrated a small region that harbors the mutations most frequently associated with rifampin resistance. Earlier reports have described a high degree of sequence conservation of rpoB amon...

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Pubblicato in:	J Clin Microbiol
Autori principali:	Whelen, A C, Felmlee, T A, Hunt, J M, Williams, D L, Roberts, G D, Stockman, L, Persing, D H
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1995
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC227990/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7751357/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jcm.33.3.556-561.1995
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