Direct genotypic detection of Mycobacterium tuberculosis rifampin resistance in clinical specimens by using single-tube heminested PCR.

Recent analysis of the gene encoding the beta subunit of Mycobacterium tuberculosis RNA polymerase (rpoB) has demonstrated a small region that harbors the mutations most frequently associated with rifampin resistance. Earlier reports have described a high degree of sequence conservation of rpoB amon...

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Detalhes bibliográficos
Main Authors: Whelen, A C, Felmlee, T A, Hunt, J M, Williams, D L, Roberts, G D, Stockman, L, Persing, D H
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC227990/
https://ncbi.nlm.nih.gov/pubmed/7751357
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