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Mutagenic analysis of the nucleation propensity of oxidized Alzheimer’s β-amyloid peptide

The formation of polypeptide aggregates represents a nucleated polymerization reaction in which an initial nucleation event (lag phase) is followed by the extension of newly formed nuclei into larger aggregates, including fibrils (growth phase). The efficiencies of these reactions relate to the lag...

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Autores principales: Christopeit, Tony, Hortschansky, Peter, Schroeckh, Volker, Gührs, Karlheinz, Zandomeneghi, Giorgia, Fändrich, Marcus
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2005
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2279324/
https://ncbi.nlm.nih.gov/pubmed/15987892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.051470405
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