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Mutagenic analysis of the nucleation propensity of oxidized Alzheimer’s β-amyloid peptide
The formation of polypeptide aggregates represents a nucleated polymerization reaction in which an initial nucleation event (lag phase) is followed by the extension of newly formed nuclei into larger aggregates, including fibrils (growth phase). The efficiencies of these reactions relate to the lag...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Cold Spring Harbor Laboratory Press
2005
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2279324/ https://ncbi.nlm.nih.gov/pubmed/15987892 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.051470405 |
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