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Tumors from rats given 1,2-dimethylhydrazine plus chlorophyllin or indole-3-carbinol contain transcriptional changes in β-catenin that are independent of β-catenin mutation status

Tumors induced in the rat by 1,2-dimethylhydrazine (DMH) contain mutations in β-catenin, but the spectrum of such mutations can be influenced by phytochemicals such as chlorophyllin (CHL) and indole-3-carbinol (I3C). In the present study, we determined the mutation status of β-catenin in more than 5...

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Detalhes bibliográficos
Main Authors: Wang, Rong, Dashwood, W. Mohaiza, Bailey, George S., Williams, David E., Dashwood, Roderick H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2279303/
https://ncbi.nlm.nih.gov/pubmed/16860348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrfmmm.2006.05.026
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