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Test of the Binding Threshold Hypothesis for olfactory receptors: Explanation of the differential binding of ketones to the mouse and human orthologs of olfactory receptor 912-93

We tested the Binding Threshold Hypothesis (BTH) for activation of olfactory receptors (ORs): To activate an OR, the odorant must bind to the OR with binding energy above some threshold value. The olfactory receptor (OR) 912-93 is known experimentally to be activated by ketones in mouse, but is inac...

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Bibliografiset tiedot
Päätekijät: Hummel, Patrick, Vaidehi, Nagarajan, Floriano, Wely B., Hall, Spencer E., Goddard, William A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Cold Spring Harbor Laboratory Press 2005
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2279295/
https://ncbi.nlm.nih.gov/pubmed/15722446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.041119705
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