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K(+)-dependent gating of K(ir)1.1 channels is linked to pH gating through a conformational change in the pore
1. We have used giant patch-clamp recording to investigate the interaction between pH gating and K(+)-dependent gating in rat K(ir)1.1 (ROMK) channels heterologously expressed in Xenopus oocytes. 2. Gating by intracellular protons (pH gating) and extracellular K(+) ions (K(+)-dependent gating) is a...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Blackwell Science Inc
2001
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2278684/ https://ncbi.nlm.nih.gov/pubmed/11432991 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.2001.t01-1-00049.x |
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