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Exploration of the role of reactive oxygen species in glutamate neurotoxicity in rat hippocampal neurones in culture

1. Exposure of hippocampal neurones to glutamate at toxic levels is associated with a profound collapse of mitochondrial potential and deregulation of calcium homeostasis. We have explored the contributions of reactive oxygen species (ROS) to these events, considered to represent the first steps in...

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Autors principals: Vergun, Olga, Sobolevsky, Alexander I, Yelshansky, Maria V, Keelan, Julie, Khodorov, Boris I, Duchen, Michael R
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2278451/
https://ncbi.nlm.nih.gov/pubmed/11179399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.2001.0147j.x
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