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Interaction of memantine and amantadine with agonist-unbound NMDA-receptor channels in acutely isolated rat hippocampal neurons

1. Using whole-cell patch-clamp techniques, the mechanisms of NMDA channel blockade by amino-adamantane derivatives (AADs) memantine (3,5-dimethyl-aminoadamantane, MEM) and amantadine (1-aminoadamantane, AM) have been studied in rat hippocampal neurons acutely isolated by the vibrodissociation metho...

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Bibliografiske detaljer
Main Authors: Sobolevsky, Alexander I, Koshelev, Sergey G, Khodorov, Boris I
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 1998
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2231181/
https://ncbi.nlm.nih.gov/pubmed/9729616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.1998.047bf.x
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