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A mutation of the H-loop selectively affects rhodamine transport by the yeast multidrug ABC transporter Pdr5
The yeast ABC transporter Pdr5 plays a major role in drug resistance against a large number of structurally unrelated compounds. Although Pdr5 has been extensively studied, many important aspects regarding its molecular mechanisms remain unresolved. For example, a striking degeneration of conserved...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2278221/ https://ncbi.nlm.nih.gov/pubmed/18356296 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0800191105 |
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