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Generating Symmetry in the Asymmetric ATP-binding Cassette (ABC) Transporter Pdr5 from Saccharomyces cerevisiae

Pdr5 is a plasma membrane-bound ABC transporter from Saccharomyces cerevisiae and is involved in the phenomenon of resistance against xenobiotics, which are clinically relevant in bacteria, fungi, and humans. Many fungal ABC transporters such as Pdr5 display an inherent asymmetry in their nucleotide...

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Detalhes bibliográficos
Main Authors: Gupta, Rakeshkumar P., Kueppers, Petra, Hanekop, Nils, Schmitt, Lutz
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4140885/
https://ncbi.nlm.nih.gov/pubmed/24733388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.553065
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