Activity-dependent Synaptogenesis: Regulation by a CaM-kinase kinase/CaM-kinase I/βPIX Signaling Complex

Neuronal activity augments maturation of mushroom-shaped spines to form excitatory synapses, thereby strengthening synaptic transmission. We have delineated a Ca(2+)-signaling pathway downstream of the NMDA receptor that stimulates calmodulin-dependent kinase kinase (CaMKK) and CaMKI to promote form...

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Hlavní autoři: Saneyoshi, Takeo, Wayman, Gary, Fortin, Dale, Davare, Monika, Hoshi, Naoto, Nozaki, Naohito, Natsume, Tohru, Soderling, Thomas R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2277504/
https://ncbi.nlm.nih.gov/pubmed/18184567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2007.11.016
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