Regulation of Neuronal mRNA Translation by CaM-Kinase I Phosphorylation of eIF4GII

Ca(2+)/calmodulin-dependent kinases (CaMKs) are essential for neuronal development and plasticity, processes requiring de novo protein synthesis. Roles for CaMKs in modulating gene transcription are well established, but their involvement in mRNA translation is evolving. Here we report that activity...

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Detalhes bibliográficos
Main Authors: Srivastava, Taasin, Fortin, Dale A., Nygaard, Sean, Kaech, Stefanie, Sonenberg, Nahum, Edelman, Arthur M., Soderling, Thomas R.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3346851/
https://ncbi.nlm.nih.gov/pubmed/22514323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0030-12.2012
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