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Rapid CB(1) cannabinoid receptor desensitization defines the time course of ERK1/2 MAP kinase signaling

Molecular mechanisms regulating the development of physiological and behavioral tolerance to cannabinoids are not well understood. Two cellular correlates implicated in the development and maintenance of tolerance are CB(1) cannabinoid receptor internalization and uncoupling of receptor signal trans...

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Detalhes bibliográficos
Main Authors: Daigle, Tanya L., Kearn, Christopher S., Mackie, Ken
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2277473/
https://ncbi.nlm.nih.gov/pubmed/17681354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2007.06.005
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