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Rapid CB(1) cannabinoid receptor desensitization defines the time course of ERK1/2 MAP kinase signaling
Molecular mechanisms regulating the development of physiological and behavioral tolerance to cannabinoids are not well understood. Two cellular correlates implicated in the development and maintenance of tolerance are CB(1) cannabinoid receptor internalization and uncoupling of receptor signal trans...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2007
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2277473/ https://ncbi.nlm.nih.gov/pubmed/17681354 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2007.06.005 |
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