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The RXRα C-terminus T462 is a NMR sensor for coactivator peptide binding
The C-terminal activation function-2 (AF-2) helix plays a crucial role in retinoid X receptor alpha (RXRα)-mediated gene expression. Here, we report a nuclear magnetic resonance (NMR) study of the RXRα ligand-binding domain complexed with 9-cis-retinoic acid and a glucocorticoid receptor-interacting...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2277333/ https://ncbi.nlm.nih.gov/pubmed/18088598 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2007.12.051 |
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