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The NMR structure of a stable and compact all-β-sheet variant of intestinal fatty acid-binding protein

Intestinal fatty acid-binding protein (I-FABP) has a clam-shaped structure that may serve as a scaffold for the design of artificial enzymes and drug carriers. In an attempt to optimize the scaffold for increased access to the interior-binding cavity, several helix-less variants of I-FABP have been...

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Detalhes bibliográficos
Main Authors: Ogbay, Benhur, Dekoster, Gregory T., Cistola, David P.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2286757/
https://ncbi.nlm.nih.gov/pubmed/15096629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.03546204
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