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Low-affinity spermine block mediating outward currents through Kir2.1 and Kir2.2 inward rectifier potassium channels

The outward component of the strong inward rectifier K(+) current (I(Kir)) plays a pivotal role in polarizing the membranes of excitable and non-excitable cells and is regulated by voltage-dependent channel block by internal cations. Using the Kir2.1 channel, we previously showed that a small fracti...

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Autores principales: Ishihara, Keiko, Yan, Ding-Hong
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2277198/
https://ncbi.nlm.nih.gov/pubmed/17640933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2007.136028
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