Reorganized stores and impaired calcium handling in skeletal muscle of mice lacking calsequestrin-1

Calsequestrin (CS), the major Ca(2+)-binding protein in the sarcoplasmic reticulum (SR), is thought to play a dual role in excitation–contraction coupling: buffering free Ca(2+) increasing SR capacity, and modulating the activity of the Ca(2+) release channels (RyRs). In this study, we generated and...

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Detalhes bibliográficos
Main Authors: Paolini, Cecilia, Quarta, Marco, Nori, Alessandra, Boncompagni, Simona, Canato, Marta, Volpe, Pompeo, Allen, Paul D, Reggiani, Carlo, Protasi, Feliciano
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2007
Assuntos:
Skeletal Muscle And Exercise
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2277031/
https://ncbi.nlm.nih.gov/pubmed/17627988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2007.138024
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