Natural killer cells are required for accelerated type 1 diabetes driven by interferon-β

The destruction of β cells by the islet infiltrating lymphocytes causes type 1 diabetes. Transgenic mice models expressing interferon (IFN)-β in β cells, in the non-obese diabetic (NOD) strain and in a diabetes-free, major histocompatibility complex-matched, homologous strain, the non-obese resistan...

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Hlavní autoři: Alba, A, Planas, R, Clemente, X, Carrillo, J, Ampudia, R, Puertas, M-C, Pastor, X, Tolosa, E, Pujol-Borrell, R, Verdaguer, J, Vives-Pi, M
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2008
Témata:
Basic Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2276969/
https://ncbi.nlm.nih.gov/pubmed/18190608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2007.03580.x
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