Natural killer cells are required for accelerated type 1 diabetes driven by interferon-β

The destruction of β cells by the islet infiltrating lymphocytes causes type 1 diabetes. Transgenic mice models expressing interferon (IFN)-β in β cells, in the non-obese diabetic (NOD) strain and in a diabetes-free, major histocompatibility complex-matched, homologous strain, the non-obese resistan...

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Bibliographic Details
Main Authors: Alba, A, Planas, R, Clemente, X, Carrillo, J, Ampudia, R, Puertas, M-C, Pastor, X, Tolosa, E, Pujol-Borrell, R, Verdaguer, J, Vives-Pi, M
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2008
Subjects:
Basic Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2276969/
https://ncbi.nlm.nih.gov/pubmed/18190608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2007.03580.x
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