Stable cell lines expressing high levels of the herpes simplex virus type 1 LAT are refractory to caspase 3 activation and DNA laddering following cold shock induced apoptosis

Antzeko izenburuak

• The herpes simplex virus type 1 (HSV-1) latency-associated transcript (LAT) protects cells against cold-shock-induced apoptosis by maintaining phosphorylation of protein kinase B (AKT)
  nork: Carpenter, Dale, et al.
  Argitaratua: (2015)
• Increased neurovirulence and reactivation of the herpes simplex virus type 1 latency associated transcript (LAT) negative mutant dLAT2903 with a disrupted LAT miR-H2
  nork: Jiang, Xianzhi, et al.
  Argitaratua: (2015)
• Introducing point mutations into the ATGs of the putative open reading frames of the HSV-1 gene encoding the latency associated transcript (LAT) reduces its anti-apoptosis activity
  nork: Carpenter, Dale, et al.
  Argitaratua: (2007)
• The Herpes Simplex Virus Type 1 Latency-Associated Transcript Can Protect Neuron-Derived C1300 and Neuro2A Cells from Granzyme B-Induced Apoptosis and CD8 T-Cell Killing
  nork: Jiang, Xianzhi, et al.
  Argitaratua: (2011)
• Large Amounts of Reactivated Virus in Tears Precedes Recurrent Herpes Stromal Keratitis in Stressed Rabbits Latently Infected with Herpes Simplex Virus
  nork: Perng, Guey-Chuen, et al.
  Argitaratua: (2015)