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Recognition of Trimethylated Histone H3 Lysine 4 Facilitates the Recruitment of Transcription Post-Initiation Factors and pre-mRNA Splicing

Tri-methylation of histone H3 on lysine 4 (H3K4me3) localizes near the 5′ region of genes and is tightly associated with active loci. Several proteins, such as CHD1, BPTF, JMJD2A, and the ING tumor suppressor family, directly recognize this lysine methyl mark. However, how H3K4me3 recognition partic...

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Detalhes bibliográficos
Main Authors: Sims, Robert J., Millhouse, Scott, Chen, Chi-Fu, Lewis, Brian A., Erdjument-Bromage, Hediye, Tempst, Paul, Manley, James L., Reinberg, Danny
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2276655/
https://ncbi.nlm.nih.gov/pubmed/18042460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2007.11.010
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