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Lysosome-targeted stress reveals increased stability of lipofuscin-containing lysosomes
Cellular ageing is associated with accumulation of undegradable intralysosomal material, called lipofuscin. In order to accelerate the lipofuscin accumulation, confluent, growth-arrested human fibroblasts were cultured under hyperoxic conditions. To provide a better insight into the effects of lipof...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Springer Netherlands
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2276591/ https://ncbi.nlm.nih.gov/pubmed/19424871 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-007-9045-9 |
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