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Lysosome-targeted stress reveals increased stability of lipofuscin-containing lysosomes

Cellular ageing is associated with accumulation of undegradable intralysosomal material, called lipofuscin. In order to accelerate the lipofuscin accumulation, confluent, growth-arrested human fibroblasts were cultured under hyperoxic conditions. To provide a better insight into the effects of lipof...

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Hlavní autoři: Stroikin, Yuri, Mild, Hanna, Johansson, Uno, Roberg, Karin, Öllinger, Karin
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Netherlands 2008
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2276591/
https://ncbi.nlm.nih.gov/pubmed/19424871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-007-9045-9
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