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The in Vivo Rate of Somatic Adenomatous Polyposis Coli Mutation
Cancer arises through successive somatic mutations/epimutations of oncogenes and tumor-suppressor genes. Accurate estimates of the rates at which these (epi)mutations occur are a vital but missing link in our emerging quantitative understanding of tumorigenesis. Their absence has hindered arguments...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Investigative Pathology
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2276411/ https://ncbi.nlm.nih.gov/pubmed/18321998 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.070724 |
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