A hypomorphic mouse model of dystrophic epidermolysis bullosa reveals mechanisms of disease and response to fibroblast therapy

Dystrophic epidermolysis bullosa (DEB) is a severe skin fragility disorder associated with trauma-induced blistering, progressive soft tissue scarring, and increased risk of skin cancer. DEB is caused by mutations in type VII collagen. In this study, we describe the generation of a collagen VII hypo...

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Bibliografische gegevens
Hoofdauteurs: Fritsch, Anja, Loeckermann, Stefan, Kern, Johannes S., Braun, Attila, Bösl, Michael R., Bley, Thorsten A., Schumann, Hauke, von Elverfeldt, Dominik, Paul, Dominik, Erlacher, Miriam, Berens von Rautenfeld, Dirk, Hausser, Ingrid, Fässler, Reinhard, Bruckner-Tuderman, Leena
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 2008
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2276400/
https://ncbi.nlm.nih.gov/pubmed/18382769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI34292
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