HIV-1 Nef Disrupts the Podocyte Actin Cytoskeleton by Interacting with Diaphanous Interacting Protein

The ability of the human immunodeficiency virus, type 1 (HIV-1) protein Nef to induce cytoskeleton changes in infected host cells is a key event in viral replication. In renal podocytes, we found that Nef induced loss of stress fibers and increased lamellipodia, pathological changes leading to prote...

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Detalhes bibliográficos
Main Authors: Lu, Ting-chi, He, John Cijiang, Wang, Zhao-hui, Feng, Xiaobei, Fukumi-Tominaga, Tomoko, Chen, Nan, Xu, Jin, Iyengar, Ravi, Klotman, Paul E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Mechanisms of Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2276381/
https://ncbi.nlm.nih.gov/pubmed/18234668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M708920200
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