Nef interaction with actin compromises human podocyte actin cytoskeletal integrity

The HIV-1 accessory protein Nef is considered to play an important role in the development of podocyte phenotype in HIV-1 associated nephropathy. We hypothesized that Nef may be altering podocyte phenotype both structurally and functionally. To elucidate the involved mechanisms, podocyte proteins in...

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Bibliografiske detaljer
Main Authors:	Tan, Raymond, Patni, Hitesh, Tandon, Pranai, Luan, Liming, Sharma, Bipin, Salhan, Divya, Saleem, Moin A., Mathieson, Peter W., Malhotra, Ashwani, Husain, Mohammad, Upadhya, Poornima, Singhal, Pravin C.
Format:	Artigo
Sprog:	Inglês
Udgivet:	2012
Fag:	Article
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3463768/ https://ncbi.nlm.nih.gov/pubmed/22721673 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexmp.2012.06.001
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Nef interaction with actin compromises human podocyte actin cytoskeletal integrity

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