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TOLL-LIKE RECEPTORS STIMULATE REGULATED INTRAMEMBRANE PROTEOLYSIS OF THE CSF-1 RECEPTOR THROUGH ERK ACTIVATION
The CSF-1 receptor is a protein-tyrosine kinase that regulates the renewal, differentiation and activation of monocytes and macrophages. We have recently shown that the CSF-1 receptor undergoes regulated intramembrane proteolysis, or RIPping. Here, we report that RIPping can be observed in response...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2276177/ https://ncbi.nlm.nih.gov/pubmed/18294963 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2008.02.029 |
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