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T Cells of Different Developmental Stages Differ in Sensitivity to Apoptosis Induced by Extracellular NAD

Extracellular nucleotides such as ATP and NAD can profoundly affect the functions of lymphocytes, macrophages, and other cells. We have recently shown that extracellular NAD induces rapid apoptosis in naive T cells by a mechanism involving the ADP-ribosylation of cell surface molecules. In the prese...

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Autors principals: Haag, Friedrich, Freese, Dunja, Scheublein, Felix, Ohlrogge, Wiebke, Adriouch, Sahil, Seman, Michel, Koch-Nolte, Friedrich
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2002
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2276114/
https://ncbi.nlm.nih.gov/pubmed/15144016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10446670310001593514
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