Differential Effects of X-Irradiation and Cyclosporin-A Administration on the Thymus with Respect to the Generation of Cyclosporin-A-Induced Autoimmunity

Cyclosporin A (CsA), a potent inhibitor of T-cell activation, has been shown to have several effects on thymocyte maturation, thymic stromal cells, and the generation of autoreactive T cells. In Lewis rats, the combination of lethal irradiation, syngeneic bone marrow transplantation, and a 4-week co...

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Detalhes bibliográficos
Main Authors: Beijleveld, Leo J.J., Damoiseaux, Jan G.M.C., Van Breda Vriesman, Peter J.C.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 1995
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275949/
https://ncbi.nlm.nih.gov/pubmed/9700362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/1995/18495
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